PGT-SR
PGT-SR (Pre-implantation Genetic Testing for Structural Chromosomal Rearrangements) is an integral component of our comprehensive IVF treatment at Angel Fertility Clinic. This genetic test is performed on embryos created through IVF to screen for chromosomal structural rearrangements caused by inversions and balanced translocations. Using pioneering AI analysis with real outcome data, we employ two independent analyses (CNV and SNP) to identify unbalanced chromosomal rearrangements, offering full confidence in accurate and robust results for improving your chances of establishing a healthy pregnancy.
Treatment Process
Embryo Creation
Embryos are created through the IVF procedure, following standard protocols for fertilization and early development.
Genetic Material Collection
A few cells are carefully removed from each embryo for genetic testing without harming the embryo's development potential.
AI-Powered Analysis
Two independent analyses using CNV (Copy Number Variation) and SNP (Single Nucleotide Polymorphism) are performed to identify unbalanced chromosomal rearrangements with high accuracy.
Testing for Rearrangements
The three primary types of rearrangements tested are: Reciprocal translocation, Robertsonian translocation, and Inversion. Results identify embryos with correct chromosomal material.
Normal Embryo Selection
Only embryos with normal chromosomal structure are selected for transfer, ensuring the highest chance of successful pregnancy and healthy birth.
Embryo Transfer
Our fertility experts confidently transfer one embryo at a time, improving chances of a successful IVF cycle while reducing risks.
Key Benefits
- Identifies embryos with correct chromosomal material
- Improves chances of successful pregnancy and healthy birth
- Reduces risk of miscarriage significantly
- Prevents chromosomal disorders in offspring
- Reduces chances of fraternal twins and related complications
- AI-powered analysis with CNV and SNP for accuracy
- Can be performed with PGT-A for comprehensive screening
- Enables confident single embryo transfer
Who Is This For?
- People suffering from chromosomal rearrangements
- Carriers of Reciprocal translocation
- Carriers of Robertsonian translocation
- Carriers of Inversion
- Those who had a previous pregnancy with chromosome rearrangement
- Parents who had a child with chromosome rearrangement
- Couples at risk of creating embryos with improper chromosome numbers
- Patients seeking to improve IVF success rates
Frequently Asked Questions
What is PGT-SR?
What is PGT-SR?
PGT-SR stands for Pre-implantation Genetic Testing for Structural Chromosomal Rearrangements. It's a genetic test performed on embryos created through IVF to screen for chromosomal structural arrangements caused by inversions and balanced translocations. It was formerly known as PGD (Pre-implantation Genetic Diagnosis).
Who should consider PGT-SR testing?
Who should consider PGT-SR testing?
PGT-SR is mainly for people suffering from chromosome rearrangements who are at risk of creating embryos with improper chromosome numbers or structure. You should consider it if you or your partner is a carrier of inversion, Robertsonian translocation, or Reciprocal translocation, or if you had a previous pregnancy or child with chromosome rearrangement.
How does PGT-SR work?
How does PGT-SR work?
PGT-SR involves testing embryos created through IVF using pioneering AI analysis with two independent analyses (CNV and SNP). It identifies embryos with correct chromosomal material that are likely to lead to successful pregnancy and healthy birth. The three primary types of rearrangements tested are inversion, Robertsonian translocation, and Reciprocal translocation.
Can PGT-SR be combined with other tests?
Can PGT-SR be combined with other tests?
Yes, we often perform PGT-SR with PGT-A (Pre-implantation Genetic Testing for Aneuploidy) for comprehensive embryo screening. This combination checks embryos for both structural rearrangements and chromosome number abnormalities, providing the most thorough assessment.
What are the benefits of PGT-SR at Angel Fertility Clinic?
What are the benefits of PGT-SR at Angel Fertility Clinic?
At Angel Fertility Clinic, we use AI-powered analysis with real outcome data and dual independent analyses (CNV and SNP) for accurate and robust results. Our well-trained fertility experts can confidently transfer embryos one at a time, improving your chances of successful IVF while reducing risks of miscarriage, chromosomal disorders, and other abnormalities. Contact us at info@angelfertilityclinic.com for more details.